We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation every day to make the world a more healthy place. This was Charles Pfizer's initial vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best talent, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and embodies the value we work to bring to patients and society. Our purpose makes certain that patients continue to be at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, partnering with others in the healthcare system to improve access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.