We are in relentless pursuit of breakthroughs that improve patients' lives. We drive innovation each day to make the world a healthier place. This was Charles Pfizer's founding vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more innovative, recruit and maintain the best people, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and reflects our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and reflects the value we aim to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We fulfill our purpose by finding the best science in the world, working with others in the healthcare system to increase access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.